Gonorrhoea could become ‘untreatable’ as cases of the STI reach record level

Gonorrhoea, a sexually transmitted infection (STI), is reaching alarming levels globally, with health experts warning that it could become “untreatable” due to increasing antibiotic resistance. The rise in cases, coupled with the growing resistance of the bacteria to available treatments, has prompted serious concerns among medical professionals and public health organizations.

Record Levels of Gonorrhoea

  • Global Increase:
  • Reports indicate that cases of gonorrhoea have surged to record highs in many countries. For instance, in the UK, the number of reported gonorrhoea cases has reached its highest level since records began. Similarly, other regions, including the United States, Europe, and parts of Asia, have also seen significant increases.
  • Contributing Factors:
  • Several factors contribute to this rise, including increased sexual activity without protection, reduced use of condoms, more accessible STI testing, and a lack of awareness or education about the risks of STIs. The COVID-19 pandemic also disrupted sexual health services, potentially leading to undiagnosed or untreated cases that have contributed to the spread of the infection.

Antibiotic Resistance and the Threat of Untreatability

  • Antibiotic Resistance:
  • Gonorrhoea is caused by the bacterium Neisseria gonorrhoeae, which has progressively developed resistance to multiple classes of antibiotics. Over the decades, the bacterium has become resistant to drugs such as penicillin, tetracycline, and fluoroquinolones, leaving fewer effective treatment options.
  • Current Treatments at Risk:
  • The current standard treatment for gonorrhoea involves a combination of antibiotics, typically ceftriaxone (an injectable cephalosporin) and azithromycin. However, strains of gonorrhoea resistant to these antibiotics have been detected in several countries, raising fears that the infection could soon become untreatable.
  • Super Gonorrhoea:
  • “Super gonorrhoea” refers to strains of Neisseria gonorrhoeae that are resistant to all or nearly all available antibiotics. These cases are still rare but are increasing, making it harder for healthcare providers to treat the infection effectively. The World Health Organization (WHO) has classified antibiotic-resistant gonorrhoea as a high-priority pathogen due to the serious threat it poses to public health.

Implications of Untreatable Gonorrhoea

  • Health Consequences:
  • If gonorrhoea becomes untreatable, it could lead to severe health complications, including pelvic inflammatory disease (PID) in women, which can cause infertility, ectopic pregnancy, and chronic pelvic pain. In men, untreated gonorrhoea can result in epididymitis, which may also lead to infertility. Additionally, untreated gonorrhoea can increase the risk of HIV transmission.
  • Public Health Impact:
  • The spread of untreatable gonorrhoea would represent a major public health crisis, potentially leading to a resurgence of the disease with severe outcomes. The cost of managing complications and the burden on healthcare systems could be substantial.

Efforts to Combat the Threat

  • Research and Development:
  • There is an urgent need for the development of new antibiotics and alternative treatments for gonorrhoea. Several pharmaceutical companies and research institutions are working on developing new drugs, but these efforts are still in the early stages. Additionally, research into vaccines for gonorrhoea is ongoing, though no vaccine has yet been approved.
  • Prevention and Awareness:
  • Public health campaigns are crucial in raising awareness about the risks of gonorrhoea, the importance of safe sexual practices, and the need for regular STI testing. Increased use of condoms and reducing risky sexual behavior are key strategies in preventing the spread of the infection.
  • Global Surveillance:
  • Enhanced surveillance and monitoring of antibiotic resistance patterns are essential to track the spread of resistant gonorrhoea strains. This can help inform treatment guidelines and public health interventions.

Conclusion

The rising threat of antibiotic-resistant gonorrhoea, with the potential to become untreatable, represents a significant global health challenge. As cases reach record levels, the medical community is sounding the alarm about the urgent need for new treatments, increased prevention efforts, and greater public awareness. Without immediate action, the implications for individual and public health could be dire, underscoring the critical need for a coordinated global response.

  • Muthomi Ireri

    Manager, Planet GIM

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