Scientists from Imperial College London have potentially made a groundbreaking discovery in anti-ageing research, suggesting a way to extend human lifespan by up to 25%. Their study, published in the journal Nature, focused on interleukin-11 (IL-11), a protein that, when switched off in experiments on mice, showed promising effects. The treated mice lived on average 155 weeks compared to 120 weeks for untreated mice, demonstrating fewer cancers, improved metabolism, hearing, vision, lung function, muscle strength, and even prevention of hair greying and loss.
Professor Stuart Cook from Imperial College’s Medical Research Council Laboratory of Medical Science described the findings as “very exciting,” noting that the treated mice showed reduced signs of ageing and frailty, alongside improved overall health.
The IL-11 gene, originally adapted from fish millions of years ago, is believed to contribute to tissue scarring, inflammation, and ageing-related diseases in humans today, despite its historical benefits like limb regeneration in certain species.
While these advancements are currently based on animal studies, researchers are optimistic about potential applications for human ageing. Meanwhile, other studies, such as those from Harvard Medical School and MIT, are exploring pills that could rejuvenate human cells and potentially treat age-related illnesses without the need for gene therapy. These developments collectively represent significant strides in the quest to enhance human longevity and quality of life.